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Role of Cyclooxygenase 2 (COX-2) in Prognosis of Breast Cancer
COX-2 regulates tumour growth, invasion and metastasis in breast cancer. This study investigated the association between COX-2 expression in human breast cancer versus the expression of ER, PR, HER-2/neu, as well as its association with other established prognostic indicators like age, menopausal status, tumour size, lymph nodal status, stage, grade, NPI and histological subtype, and aims to validate the role of overexpression of COX-2 as a prognostic marker in patients with breast cancer in Indian subcontinent. Read More
Mithramycin A Sensitizes Therapy-Resistant Breast Cancer Stem Cells
Chemotherapy resistance is a major clinical challenge for the management of locally advanced breast cancer. Accumulating evidence suggests a major role of cancer stem cells (CSCs) in chemoresistance evoking the requirement of drugs that selectively target CSCs in combination with chemotherapy. Read More
Effectiveness Of The Lockdown Model In Coronavirus Disease 2019 Pandemic
It has been declared Coronavirus (COVID–19) pandemic by the World Health Organization, which exhibited human–to–human transmissibility and spread rapidly across countries. Present study to find any association effectiveness of the lockdown in Coronavirus Disease 2019 Pandemic in the India vs world Country that are most affected. Read More